Microbiology

Agbaje-Daniels Folashade (Ph.D.)
            Ag. Head, Biological Sciences

Welcome

The Department is fully committed to the dissemination of knowledge with godliness in line with the main goal of Crawford University. Lecture delivery is stylish with adequate technological advancement thereby enhancing the critical reasoning of our students. Academic curricular are regularly updated with compliance to fast evolution of knowledge and development in the fields of Life Sciences. Lecture materials and practical manuals are also rich and well packaged with relevant knowledge application. The department is blessed with a cross section of dedicated and well qualified academic staff with profound passion to impact knowledge and are given to the making of outstanding graduates that are ready to take the world by storm. This department has produced a total of 138 graduates to date with 19 in the First class including the best graduating student during the 2014/2015 convocation.

There are several ongoing researches in the two academic Programmes comprising of different areas of academic research in Life Sciences. These include drug discovery, plant pathogenesis, antimicrobial resistance monitoring within the environment and the community especially amongst healthy individuals, biochemical toxicology, toxicological studies of crude extracts of plants and algae, drug metabolism, immunochemistry, enzymology, lipid and environmental biochemistry, membrane biochemistry research and many more……APPLY NOW

Microbiology Programme

Philosophy and Objectives

PhilosophyObjectivesAdmission Requirements.
The programme is designed to provide thorough, broad and good foundation in Microbiology as it is one of the most important fields of Biological Sciences.  To prepare the students for career prospects in Medicine, Agriculture, Industry as well as Biotechnology in general. Some of the most important diseases of human, animal and plants are generally caused by microorganisms while at the same time many play major roles in soil fertility, human health and immunity, drug discovery and many other large scale industrial processes. To also expose the students to modern microbiological techniques that are required in setting up small scale industry, thereby making them to be self-reliant.Programme’s areas of specializations include Food Microbiology, Environmental and Industrial Microbiology, Medical Microbiology, Pharmaceutical Microbiology and Parasitology.

  • To make the students to be better informed about microbiological phenomenon as well as apply the information and knowledge gained towards an improved understanding of man, society and universe.
  • To provide the students with basic microbiological skills and field experience.
  • To prepare the students for careers in industries, Agriculture, Medical fields and Environmental Sciences.
  • To ensure that undergraduates who want to pursue advanced research programs in Microbiology or related courses are adequately prepared.
  • The undergraduate program in Microbiology at Crawford University is therefore designed to train students in Microbiological techniques and to give a basic knowledge of the fundamentals of Bacteriology, Mycology and Virology as well as their relationship with other disciplines. Students will be exposed to both pure and applied courses in Microbiology, backed up with appropriate practical experiences so they are prepared ahead for work in various sector of the economy. The programme encourages independence and self-confidence so that the students are able to make meaningful contributions in whatever professional activity they may become engaged. It offers sufficient depth in enabling the promising graduates to undertake postgraduate work in Microbiology and related disciplines in pure and applied sciences.

Candidate for admission into 4 year degree programme in the Department of Biological Science, Microbiology Programme, must have five subjects at the credit level in the SSCE or its equivalent including English language, Mathematics, Biology, Chemistry and Physics.


COURSE CONTENTS

100 Level

Harmmattan Semester

BIO 111         General Biology I                                 3          Credits

History of Biology. Characteristics and classification of living things. Cellular basis of life, structure and organization of plant and animal cells. Functions of cells and cell organelles. Cell division, General reproduction.  The inter-relationships of organisms. Heredity and Evolution. Elements of ecology and habitats.

Factors controlling the distribution of animals. Communities and populations. Man and environment. 30h, 45h(P).

BIO 113     General Biology I Practical                                   1 Credit


Rain Semester

BIO 112         General Biology ІІ                         3   Credits

Varieties of life. Nomenclature and classification of animals. Diagnostic features of ten major animal phyla and their classes. Structure and functions of organs and organ systems in vertebrates e.g. Rat.

Diversity, morphology and general characteristics of viruses, bacteria, fungi, algae, bryophytes, pteridophytes, gymnosperms, angiosperms structure and functions of main organs in angiosperms.

30h (T). 45h (P)

BIO 114     General Biology II Practical                            1  Credit


200 Level

Harmmatan Semester

BIO 205         Lower Invertebrate

The logy of Amoeba, paramecium. Plasmodium; Leucosolenia, Obelia, hydra, Aurel

Actinia, Dugesia, Fasciola, tenia, Ascaris, Hyperriodirilus, nereis, Hirudo, Achachatina.

Aspatheria,Sepia, macrobrachium, Lycosa, Polydesmus, Periplaneta and Asterepecten-to illustrate the classification organization, evolutionalry trends and divers of invertebrates.

30h (T) 45h (P)

BCH 211  Structure and Chemistry of Macromolecules  3          Credits

Biological membrane. Chemistry and structure of Amino acids and proteins. Chemistry of and structure of lipids. Chemistry and structure of carbohydrates. Membrane fluidity. Transport in membrane. Vitamins and Co-enzymes.

 MCB 201.      General Microbiology                              3     Credits

Pure and Applied aspects of Microbiology.  Organization of prokaryotic and eukaryoti cells. Structure, general characteristics and reproduction of viruses, bacteria and fungi.  Systematic classification of microorganisms. General methods for studying the specified groups. Microbial variation and heredity.  Economic importance of Microorganisms

MCB 203       Basic Techniques in Microbiology                 2    Credits

Culturing of microorganisms; preparation of media for microbial growth. Isolation of pure culture; streaking pour plates etc; sub culturing procedures. Staining techniques for differentiation of microorganisms. Enumeration of Microorganisms, direct and indirect procedures. Identification of microorganisms to include colonial and cellular morphology and biochemical procedures. 45h (P):

MCB 205       Basic Invertebrate Zoology                        3     Credits

The logy of Amoeba, Paramecium. Plasmodium; Leucosolenia, Obelia, Hydra, Aurel Actinia, Dugesia, Fasciola, Tenia, Ascaris, Hyperiodirilus, Nereis, Hirudo, Achachatina. Aspatheria, Sepia, Macro-brachium, Lycosa, Poly-desmus, Peri-planeta and Asterepecten – to illustrate the classification organisation, evolutionary trends and divers of invertebrates.

 MCB 207       Microbial Taxonomy and Nomenclature       1 Credit

Introduction and overview. Microbial identification, naming and classification. Sytematics and new molecular techniques. Domains of living organisms- Eubacteria, Archaea and Eukarya. Taxonomic ranking, Classification Systems- Natural and Phenetic systems. Numerical Taxonomy. Major Characteristics Used in Taxonomy. Major Characteristics Used in Taxonomy. Classical characteristics and Genetic characteristics.


Rain Semester

BIO 202  General Ecology

Concept and definition of ecosystem, ecology at community level, ecological classification of habit types, terrestrial and aquatic biomass, specific features of each. Biotic components of habitat. Natural destruction, Commnuities and population, factors of communities, success of community interaction, natural cycle, dynamics of population. Succession and climax.      30h (T) 45h (P)

BIO 204         Introductory Physiology           2          Credits  

Physical and chemical processes in basic plants and animal physiology. Basic elements of respiration, photosynthesis, transportation or circulation. Reproduction, germination, growth, hormones and Enzymology.

BIO 206       Systematics and Morphology of Plants        2      Credits

Comparative vegetative and reproductive morphology of gymnosperms and angiosperms. Heterospory and the concept of the seed. Classification of selected angiosperm families.

 BIO 208         Introductory Genetics and Evolution            3    Credit

Principles of inheritance, structure and behaviour of chromosomes. Nucleic acid and genes. Sex determination. Gene action variation. Hereditable and non-hereditable characteristics, Probability and test of goodness of quantitative inheritance. Variation in genome structure, introduction to population genetics.  Evolution and speciation.

BIO 210         Basic Chordate Zoology                           3      Credits

The biology of Balanoglossus, Ciema, Branchiostoma, Petromyzon, Scolidon, Tilapia, Bufo, Agama, Colubia and Rattus to illustrate the classification, organisation evolutionary trends and diversity of chordates.

MCB 202       General Microbiology II                                           3  Credits


300 LEVEL

Harmmatan Semester

BIO 305         Economic Botany.

Botanical characterristics, cultivationanduseds of economic plants in nigerial-fibre, rubber, oil cocoa, coffee, kola, grains, pulses, tubers, vegetables etc. Toxicological and phyrmaceutical importance of plant products

30h (T); 45(P)

BIO 301         Biology of Tropical parasites

General concept of parasitism. Host-parasite relationship. Classification, morphology, life cycles and adaptations of selected protozoan platyhelminth and nematode parasites

30h (T) 45 (P)

MCB 301       Microbial Physiology and Metabolism       3   Credits

Dynamics of growth. Nutrition and energy metabolism of microorganisms. Effect of physical and chemical factors on growth. Biochemistry of various microbial processes such as transport, regulation and respiration. Biosynthesis of microbial products. Buffer preparation and standardization. Basic separation techniques in microbiology, dialysis, salting out, gel filtration, electrophoresis etc. assay techniques for various metabolites including microbial enzymes, acids etc.

MCB 307       Immunology                                           3          Credits

Introduction. Historical background. Innate and acquired immunity. Antigens, antibodies, cellular immunity. Immunological tolerance and suppression. Surgical grafting. Complement system. Hypersensitivity. Immunological anomalies. Diagnostic immunology, Vaccines, effectors systems of parasite killing and nature of resistance in plants.

MCB 305    Microbial Genetics and Molecular Biology     3      Credits

Principles of genetic analysis, Plasmids and transposable genetic elements, mutagenesis and DNA repairs, bacteriophage genetics and genetics of Nitrogen fixation. Mechanism and nature of mutation, induction, isolation and characterization of mutants. Genetic recombination in prokaryotes including transformation, transduction, phage conversion and conjugation. Recent techniques in microbial genetics. Chemical coding and expression of genetic information. Fungal genetics. Principles and application of genetic engineering.

MCB 309       Bacteriology                                       3   Credits

Prokaryotic structure and function. Bacterial growth and nutrition. Classification, isolation and characterization of principal groups of bacteria. Special group of bacteria and their uniqueness.

MCB 313       Virology                                              2          Credits

Structure, properties and classification of viruses. Principles of isolation, cultivation and maintenance of plant and animal cells in vivo. Application of cell culture technique in virology. Viruses as agents of diseases in animals.


Rain Semester      

MCB 302Biodeterioration                                          2          Credits

Principles of microbial deterioration of materials. Material subject to microbial deterioration: Foods, jet fuels, paper, paints, textiles and leather, metals etc. Factors favouring deterioration of materials. Major microbial groups involved in the deterioration. Impact of processing and new technologies on bio deterioration. Bio deterioration control.

MCB 304      Medical Virology                         2 Credits 

Introduction and overview. Classification of viruses. Replication Viruses implicated with human diseases, symptoms, diagnosis and management. The Retroviruses and the diseases caused. Treatment of viral diseases. Viruses and epidemics. Viral infections and genetic variations. Epidemiology of viral infections.

MCB 306        Microbial Ecology                                       3          Credits

Microorganisms and ecological theory. Symbiosis and the different types that exist. Mechanisms of adaptation of microorganisms to their environment. An overview of occurrence of microorganisms in soil, water and air. Impact assessment of microbial contamination of soil, water, and air in relation to the deterioration of the environment. Growth of microbes on cell surfaces- Biofilm and its importance. Biogeochemical cycling.

MCB 308  Mycology                                                           2  Credits

Mycological techniques. Detailed account of the systematic, morphology, reproduction and life cycles of selected fungal groups. Metabolites of fungi, Industrial uses of fungi. Fungi in medicine.

MCB 310    Medical Bacteriology                                          2  Credits

An overview of bacterial diversity. Different species of bacteria of medical importance. The different bacterial general and the bacterial diseases they cause, their diagnosis and treatment. Bacterial pathogenesis and antimicrobial resistance. Major bacterial pathogens of man.

MCB 312   Microbiological Quality Control                  3          Credits

Microbiological standards of water, foods, pharmaceutical and other industrial products. National and international agencies responsible for the establishment and implementation of standards specifications and relevant regulations. Methods of assessment.  Plant and equipment sanitation and hygiene. Quality charts according to variables and attributes.  Process quality controls.

 MCB 399       Industrial Attachment                                6          Credits

Industrial attachment in an establishment where microbiological practice is carried out for on the job training.


400 Level

Harmmatan Semester

MCB 401       Essays in Microbiology                        2          Credits

Literature review of an approved topic in microbiology plus oral presentation. 90h (P)

MCB 403       Industrial Microbiology                              3          Credits

Fermentation systems; design and use of fermenters. Microorganisms of Industrial importance. Classification of microbial products by use. Relationship between primary and secondary metabolism; characteristics, sources and strain improvement of industrial microorganism. Microbial growth and product formation in industrial processes; media for industrial fermentations. Foaming, major products of industrial Microbiology: enzyme production and immobilization; production of vitamins, amino acids, antibiotics, organic acids beer and wine etc.

30h (T); 45h (P)

MCB 405       Pathogenic Microbiology                           3          Credits

Study of some microbial pathogens of plants and animals with emphasis on those prevalent in Nigeria. The geographical distribution, isolation, identification, morphology, life cycle, source of infection, transmission and the host. Ecology, clinical manifestations of specific bacterial, viral and fungal pathogens of man.

30h (T); 45h (P); PR MCB 303

MCB 407       Plant Pathology                                     3          Credits

Basic techniques in plant pathology. Concept of diseases. Mechanisms of plant infection Host-pathogen relationship. Epiphytotics and causes. Disease forecasting. Classification of plant diseases. Pathogens Etiology and disease cycles of some economic crops in Nigeria. Practical plant protection methods involving chemicals cultural practice and biological control.

30h (T); 45h (P); PR MCB 303

MCB 409       Microbiology of Water Sewage and Air       2          Credits

Assessment of sanitary quality of water bodies. Sources of pollution, Purification system. Characterization, treatment and disposal of sewage. Sources and distribution of microbes in the air.  Dissemination and survival mechanisms. Air pollution and purification techniques. Medical and  agricultural importance of air borne microbes.

MCB 413       Pharmaceutical Microbiology                       3          Credits

Concept of growth and death in microorganisms. The chemistry of synthetic chemotherapeutic agents and antibiotics. Production and synthesis of antibiotics and antiseptics. Relationship of antimicrobial agents to different microbial groups: Gram positives, Gram negatives, spore formers etc. The mode of action and assay of antibiotics and antiseptics. Sensitivity and resistance as related to microbial physiology. Microbiological quality control in the pharmaceutical industry.

30h (T); 45h (P)


Rain Semester

MCB 404            Principles of Parasitology                      2          Credits

Evolution of parasitic mode of life. Nature of parasitism in relation to other forms of animal association. Host-parasite relationships. Epidemiological studies and control measures of importance. Tropical diseases and the role of vector in the transmission of these diseases.

30h (T); 45h (P); PR: MCB 301

MCB 406       Epidemiology and Public Health                      3          Credits

Statistical applications to epidemiology. Nature of epidemiological investigations. Spectrum of infections. Herd immunity. Latency of infections. Multi-factorial systems in epidemics. Zoonoses. Antigenic drifts. Biological products for immunization. Schedules for International control of infectious diseases.

15h (T); 45h (P); PR MCB 309

MCB 408       Soil Microbiology                                         2          Credits

The characteristics of soil environment; microbial flora and fauna of soil; microbial activities in soil. Nitrogen cycle, mineral transformation by microorganisms. Ecological relationship among soil pathogens. Effects of pesticides on soil microorganisms. Biodegradation and bio-

fuel generation. Microbiology of the rhizosphere. Importance if air borne microbes. 30h (T); 45h (P

MCB 410       Petroleum Microbiology                           2          Credits

Detailed study of carbon cycle. Theories about the genesis of fossil fuels with emphasis on microbiological influence. Prospecting for oil by means of microbial indicators. Drilling: corrosion of pipes and equipment-microbiology of the process. Effects of oil spills on microbial ecology of seas and soils. Microbial decomposition of petroleum.

MCB 412       Food Microbiology                                     2          Credits

The Micro-flora of foods, relations of microorganisms to food preservation and spoilage. Food poisoning. Emphasis on new developments in Food Microbiology; Economic consequences of microorganisms in food; exploitation of microorganisms in novel processes for the production of food ingredients.

30h (T); 45h (P)

MCB 416  Introduction to Mushroom Growing Technology   2          Credits

Biology, ecology and economic importance of mushrooms. Collection, identification and preservation of mushroom. History of mushroom cultivation. Spawn production and cropping.

30h (T); 45h (P)

MCB 499       Project                                   6          Credits

Original research into a topic of microbiological interest chosen in consultation with a supervisor and with the permission of the head of Department.

225h (P)

Biochemistry Programme staff list

NAME

QUALIFICATION

DESIGNATION

AREA OF SPECIALIZATION

Prof. S.C.U. Nwachukwu

B.SC., M.Sc., Ph.D

Professor(Associate)

Industrial and Environmental Microbiology

Prof. A.A. Ajayi

B.Sc., M.Sc., Ph.D (Ife)

Professor (Associate)

Microbial Physiology and Biotechnology.

Prof. O.A. Babalola

B.Sc., M.Sc., Ph.D

Professor (Associate)

Soil Microbiology

Dr. O.A. Ogunjobi

B.Sc., M.Sc., Ph.D (Ibadan)

Sr Lecturer  (Associate)

Environmental Microbiology, Biotechnology

Dr. (Mrs.) Adebayo-Tayo

B.Sc., M.Sc., Ph.D. (Ibadan)

Sr Lecturer (Associate)

Food Microbiology

Dr. F.V. Agbaje-Daniels

B.Sc., M.Sc. (Ife), Ph.D (Lagos)

Lecturer I

Pharmaceutical/Medical Microbiology

Dr. M.O. Adigun

B.Sc., M.Sc., Ph.D. (FUNAB)

Lecturer I

Soil Microbiology

Mrs. C.C. Okonofua

B.Sc., M.Sc.(Ibadan)

Lecturer I

Parasitology

Dr. O.A. Faboyede

B.Sc., (Ilorin) M.Sc., Ph.D (Lagos)

Lecturer II

Ethnobotany/Taxonomy

Dr. O. Afolabi

DVM (Ibadan), M.Ag. (FUNAB)

Lecturer II

Public Health


Non-Academic Staff

S/N

Names

Qualification

Status

1

Mrs. R.M. Alabi

Final DIPNIIST (ANIST) C and G (London)

Principal Technologist

2

Mr. S. Ogunkorode

N.C.E. (Secretarial
Study) and Diploma in Computer Application and Data Processing.

Departmental Secretary

3

Mrs. O. Olusegun

W.A.E.C.

Laboratory Assistant

…The Tomorrow Has Just Dawned